codon是什么意思,codon中文翻译,codon发音、用法及例句

•codon

codon发音

英:['kəʊdɒn]  美:['koʊdɒn]

英:  美:

codon中文意思翻译

n. [生物]遗传密码子

codon常见例句

1 、Keywords pseudorabies virus (PRV);G+C content;relative synonymous codon usage RSCU;bias;regulatory gene;───伪狂犬病病毒;G+C含量;同义密码子相对使用度(RSCU);偏差;调节基因;

2 、Site discrepancy of synonymous codon usage in SARS coronavirus and other viruses in Coronaviridae───SARS及其他几种冠状病毒密码子使用偏性的位点差异

3 、Moreover, species with near homology relationship on evolution share the near codon usage frequency and preference index or the similar index.───在同源性方面,在进化上比较接近的物种,基因的密码子使用频率和使用偏性指标比较接近或基本相同。

4 、RT PCR showed that all samples expressed HCP gene, only one missense mutation at codon 225 (AAC to AGC, Asn to Ser) within N terminal SH2 domain was found in an ALL patient.───RT PCR显示所有标本中都有HCP基因表达 ,仅在 1例急性淋巴细胞性白血病细胞中发现一错义突变 ,发生在HCP基因氨基末端的SH2结构域 ;

5 、Thus, codon usage bias of nuclear genes appeared to be affected by translational selection.───因此,核基因的密码子使用偏好性受到翻译选择的影响。

6 、Keywords codon usage preference;vasostatin120 180;inclusion body;refolding strategy;chick embryo chorioallantoic membrane assay;───偏爱密码子;血管内皮抑制素120-180;包涵体;变复性;鸡胚尿囊膜试验;

7 、They worked out the code and they worked out that it was arranged in threes a triplet code, with each group of three bases called a codon.─── 他们破译了密码 他们发现它是一种三联体密码 每三个碱基的组合形成一个密码子

8 、A protein called a release factor binds directly to the stop codon, causing the addition of a water molecule instead of an amino acid to the polypeptide chain.───一种叫做释放因子的蛋白质直接结合在终止密码子上,导致一个水分子而不是氨基酸被加在肽链末端。

9 、PTC124 is an orally administered small molecule that targets a type of disease-causing genetic error known as a nonsense mutation, or premature stop codon.───PTC124是一种口服式小分子化合物,它的标的是针对一些因为”无义”基因突变的疾病。

10 、Secondly, LN9912 EO gene was cloned into pGEX4T, pETSO and pMAL-p2X respectively, with strains BL21 and BL21 (DE3) codon plus, BL21(DE3) and BL21 (DE3) codon plus, TB1 and BL21 C DE3) codon plus as their corresponding expression hosts.───其次,将猪瘟兔化弱毒株(HCLV)EO基因分别**入pGEX4T,pET30,pMAL-p2X中,并分别构建了以BL21和BL21(DE3)codon plus,BL21(DE3)和BL21(DE3)codon plus,TB1和BL21(DE3)codon plus为宿主菌株的原核表达系。

11 、Furthermore, the earlier the species differentiation time on evolution, the lower the difference of the codon usage frequency and preference and the higher by contraries.───在进化上分化时间越早的物种,密码子使用频率和使用偏性的差异较小,反之则较大;

12 、And you can see that we've got some punctuation in our sentences, because it turns out that there are special codons that make something like a full stop at the end of the protein.─── 如图所示 句子中会有标点符号 因为在蛋白质链的尾端 有一些特殊的密码子起着句号的作用

13 、The precore stop codon mutation was found in 7 AsCs and 10 CAH cases.───AsC与CAH组中,前C终28变异分别为7例和10例;

14 、Codon Optimization of Antibacterial Peptide Magainin and CecA-mil Gene and Over -expression in Pichia pastoris───Magainin和cecA-mil抗菌肽基因的密码子优化及在毕赤酵母中的高效表达

15 、synonymous codon repeat sequence───同义密码子重复序列

16 、Furthermore, a fragment of 150bp from start codon ATG to 150nt showed the most variation.───从ATG至第150bp区段的核苷酸序列变异频率最高。

17 、There is terminate codon TAA of the whole ORF at the 3D coding region termination.───在3D编码区末端有整个ORF的终止密码子TAA。

18 、Analyzing the Characteristics of Start Codon in Prokaryote and Yeast Genomes───原核生物和酵母基因组中起始密码的特征分析

19 、SU-DHL-9 had homozygous deletion of p16 gene. Meanwhile, SU-DHL-1 and Daudi cell lines had mutation of the second exon of p16 gene. GAC in codon 30 mutated into AAC.───SU-DHL-9有p16基因的纯合缺失,而SU-DHL-1和Daudi细胞系有p16基因的第二外显子的突变,SU-DHL-1的测序结果为密码子30的GAC突变为AAC,密码子35的GCT突变为ACT,密码子40与41之间**入了一个C;

20 、Bias of Base Composition and Codon Usage in Pseudorabies Virus Genes───伪狂犬病病毒基因编码区碱基组成与密码子使用偏差

21 、And it turns out that there's more to genes than just strings of codons.─── 他们发现基因并非 只是一串单纯的密码子

22 、Codon Optimization and Expression of Norovirus Capsid Proteins in Insect Cells───人诺如病毒衣壳蛋白的密码子优化及在昆虫细胞中的表达

23 、signal codon───信号密码子

24 、Keywords melitten;alpha fetoprotein;adenoviruses;human;sequence homology;nucleic acid;codon;───关键词蜂毒肽;甲胎蛋白类;腺病毒;人;序列同源性;核酸;密码子;

25 、Study on the Codon Usage of Chinese Hamster Ovary Cells───中华仓鼠卵巢细胞密码子的研究

26 、Correlation Between the Mutation of the DCC Gene Codon 201 and Gastric Cancer.───DCC基因201密码子突变与胃癌相关性的研究

27 、A triplet of nucleotides; a codon.───三核苷酸,密码子

28 、Each three-letter sequence of nucleotides (or codon) stands for a specific amino acid.GCA, for example, codes for alanine, one of the 20 different amino acids found in animal organisms.───其中每三个一组的核苷酸排序(称为密码子)代表特定胺基酸,譬如GCA是丙胺酸的编码,而丙胺酸只是动物体内20种不同的胺基酸之一。

29 、The detection rates of pre-S2 start codon mutation were significantly different in different groups: from 50.00% (HCC), 39.47% (LC), 8.00% (CH), to ASC (0).───前S2起始码变异在HCC、LC组的检出率分别为50.00%、39.47%,明显高于慢性肝炎组的8.00%、慢性无症状乙型肝炎表面抗原携带者组的0(P值均

30 、Among these 10 cases of CJD patients, 8 cases are codon 129 homozygous Met/Met and 2 cases are heterozygous Met/Val. No codon129 homozygous Val/Val was found.───10例CJD中 8例为12 9密码子甲硫氨酸纯合子型 ,2例 12 9密码子甲硫氨酸和缬氨酸杂合型 ,无 12 9密码子缬氨酸纯合子型。

31 、And some base bias of the 1st and the 2nd site of a codon also are related to gene expression level as well.───发现密码子的第1位点和第2位点的某些碱基分布与基因表达水平有关。

32 、coding for the same amino acid as another codon───为作为另一个密码子的同样的氨基酸编密码的

33 、Methods and Applications of Inserting a Stop Codon into a Cloned Gene with PCR───利用PCR在已克隆基因末端添加终止密码的方法与应用

34 、The total number of nucleotides between a stop codon of rbcL gene and a HindIII site in cemA gene were 2 808 and 2 810 bp in Ae.───从rbcL基因的终止密码子到cemA基因内的HindIII位点,Ae.

35 、Between codon 40 and 41, C was inserted. SU-DHL-4 and SU-DHL-6 had bcl-2/JH fusion genes. The significance of gene conformational changes affected pathogenesis, development of malignant lymphoma cell lines was discussed.───SU-DHL-4和SU-DHL-6有bcl-2/JH基因的重排,讨论了基因结构的变化在恶性淋巴瘤细胞系发生发展中的意义。

36 、Keywords Tetrahydrofolate dehydrogenase;Cricetulus;Ovary;DNA;complementary;Codon;───四氢叶酸脱氢酶;仓鼠属;卵巢;DNA;互补;密码子;

37 、Keywords ACAT1,trans-splice,chromosome,start codon,translation,regulation;───反式剪接;染色体;翻译起始密码子;表达;调控;

38 、Correlation between Synonymous Codon Usage and the Amino Acid Sequence Contexts───同义密码子用语与氨基酸序列上下文的关联

39 、Mitochondria, the tiny power generators within all kinds of cells, have their own genomes, and many have also developed their own codon assignments.───再者,细胞内的迷你发电厂粒线体也有自己的基因组,而许多粒线体也发展出自己的密码子对应系统。

40 、The detected ratios of pre-S2 start codon and pre-S deletion mutations were significantly higher in genotype C than in genotype B (43.04% vs 1.23%, 36.71% vs 19.75%, P < 0.05, respectively).───C基因型前S2起始码变异的检出率为43.04%,高于B型的1.23%(P

41 、Among 98 mutations, there is no insertion or deletion, and Yellow cattle and Yak have the same codon bias except the isoleucine codon.───共检测到98个变异位点,未发现**入和缺失,牦牛和黄牛除了异亮氨酸以外有着相同的密码子偏好.

42 、But researchers have also documented cases in which the use of an uncommon codon appears to slow protein manufacture in a way that maximizes efficient folding.───但是也有研究报告指出使用不常见的密码子会减缓蛋白质制造的速度,反而大幅增加了摺叠的效率。

43 、We found that first, the "Kozak rule" could be confirmed and extended efficiently. The bases in position -9 (nine nucleotides upstream from the ATG codon), -8, -6, -4, -3, -2, -1, +4, +5 and +6 were included in the rule.───在大量智人mRNA序列统计分析的基础上,验证了“Kozak规则”,并进行了有效扩展,将-9,-8,-6,-4,-3,-2,-1、+4,+5,+6均纳入新的规则之中。

44 、Coding for the same amino acid as another codon.───为作为另一个密码子的同样的氨基酸编密码的.

45 、The initiation codon represents the first amino acid, N-formyl methionine, at the N terminus of the polypeptide.───即编码多肽N-端第一个氨基酸即甲硫氨酸(N-甲酸化的)的密码子。

46 、All the authors are also scientific advisers to Codon Devices in Cambridge, Mass., the first commercial enterprise launched to apply engineering principles to synthetic biology.───他们共同撰写这篇文章,是因为彼此专长各异,对生物制程的发展有不同的贡献,代表了生物工程学跨学科的特色。

47 、ambiguous codon───多义密码子

48 、Comparatively, it is the species function rather than the gene function that determines their gene codon usage patterns.───与基因的功能对密码子使用的影响相比,这些泉古菌密码子的使用偏向性更是由其物种所决定的。

49 、Introduction :About 30% of inherited genetic disorders in humans result from premature termination codon mutations.───前言:约30%的人类遗传性疾病起源于过早出现的终止密码子突变。

50 、All 13 protein coding genes (PCGs) of the G. gratiosa mitogenome start with a typical ATN codon.───优雅蝈螽线粒体基因组的13 个蛋白质编码基因均以ATN作为起始密码子;

51 、The Factors Shaping Synonymous Codon Usage in the Genome of Burkholderia mallei.───Sheng Zhao,Qin Zhang,Zhihua Chen,Yixin Zhao, Jincheng Zhong (通讯作者).

52 、Analysis of the secondary structure around the initiati on codon among three mRNAs showed that the secondary structure of the mRNA from parg-leuS was the strongest of the three mRNAs.───分析三种leuSmRNA在起始密码子附近的二级结构 ,发现从 parg leuS转录的mRNA的二级结构最强。

53 、Result1 C-kit mutation in GIST: C-kit gene mutations were found in three of eight GIST samples. The first was an insertion of 12 bps at Codon 579;───1 C-kit基因突变检测:8例GIST C-kit基因exon11测序结果显示3例含突变:1例为**入性突变,白密码子Codon 579**入12bp;

54 、codegenerate codon───互简并密码子

55 、synonymous codon───同义密码子

56 、Keywords Mannose-binding lectins;Polymerase chain reaction;Codon;Mutation;───关键词甘露糖结合凝集素类;聚合酶链反应;密码子;突变;

57 、Relations between synonymous codon usage and protein structure───同义密码子用语与蛋白质二级结构信息

58 、Frequencies of genetypes at codon 52 of MBL Exon I in healthy chinese Hans nationality───52位基因频率调查

59 、a section within a strand of messenger RNA containing a codon altered through mutation so that it codes for a different amino acid───一个RNA螺旋体中包含的一个因突变而改变密码子的部分,它能编码成为另一种不同的氨基酸

60 、The high-frequency codons were selected by high-frequency codon analysis according to relative frequency of synonymous codon (RFSC) which is calculated by RFCS program written by ourselves.───利用自编的RFCS程序计算同义密码子相对使用频率(RFSC),并根据RFSC值筛选出高频密码子。

61 、With Kozak similar sequences of triple codon AAA:specifically enhancing the immunological results of Foot-and-Mouth disease DNA vaccine───含三联密码AAA的Kozak类似序列特异性增强口蹄疫DNA疫苗的免疫效果

62 、The distance and the composition between the Shine-Dalgarno(SD)sequence and the start codon have, profound effect on the expression of prochymosin gene causing a 15fold difference.───Shine-Dalgarno序列与起始密码子之间的距离与组成对凝乳酸原基因表达有明显的影响,可导致其表达水平有15倍之差。

63 、Study on The Point Mutation at Codon 12 of H-ras Oncogene in Human Fetal Epithejial Cell Treated with ( Trans )-BPDE───反式-BPDE诱发人胎气管上皮细胞H-ras癌基因点突变的研究

64 、Having more than one codon specify the same amino acid.Used of a genetic code.───兼并密码子的有不止一个密码子来指定同样的氨基酸。

65 、The underlined nucleotides are the first upstream in-frame stop codon and the two putatie polyadenylation signals, respectiely.The asterisk indicates the stop codon.───加下划线的核苷酸分别是这个读码框中上游的第一个终止密码和两个已经认定的多核苷酸序列.星号标记的就是终止密码.

66 、Keywords Human papillomavirus type 16 L1;recombinant adenovirus;recombinant baculovirus;expression;codon optimization;virus-like particle(VLP);───人乳头瘤病毒L1;16型;重组腺病毒;重组杆状病毒;表达;密码子优化;病毒样颗粒;

67 、Keywords 3 untranslated regions/genetics;Variation(genetics);Hepacivirus/genetics;Codon;terminator;───3非翻译区/遗传学;变异(遗传学);肝炎病毒/遗传学;密码子;终止;

68 、K ras gene point mutation at codon 12 was found in human pancreatic carcinoma cell line PC 2, and the mutation style was CGT.───人胰腺癌细胞株PC 2存在K ras基因点突变 ,突变方式为CGT。

69 、Analysis of the relationship between codon frequency of prolactin gene and laying performance in five chicken breeds───五个鸡群中催乳素基因密码子使用频率与产蛋量的关系分析

70 、Comparison and Analysis of Synonymous Codon Repeat Sequences in Different Genomes───不同基因组中同义密码子重复序列的分析与比较

71 、relative synonymous codon usage───同义密码子相对使用

72 、One codon had been deciphered, and the triplet UUU became the first word in the chemical dictionary of life.───于是头一个密码解开了,UUU这三个核苷酸组成了生化字典里的第一个字。

73 、The Contrast Study of Base's Conservative Character and Correlative Character between E.coli and Yeast Gene for Adjacent Sequence of Initiation Codon or Termination Codon───E.coli和Yeast基因起始与终止密码子邻近序列碱基保守性、关联性的对比研究

74 、Comparative Study on Mutations at Codon 12 of Ki-ras Gene Between Chinese and Western Patients with Pancreatic Cancer───中国人与西方人胰腺癌组织中Ki-ras基因第12密码子突变表型的比较

75 、The style of K-ras gene point mutation at codon 12 was GAT in human pancreatic cancer cell line.───人胰腺癌细胞株PANC-1存在K-ras基因的点突变,其突变方式为CAT。

76 、multi-mutants of YIDD and codon 528. 91% codon of YMDD mutants were GTG, ATX;───YIDD、528位点同时突变。 YMDD突变密码子91%为:GTG、ATT;

77 、As gene type and function is fixed, species difference can also affect codon usage bias.The closer the consanguinity between species in evolution, the similar their codon usage bias is.───在基因的类型和功能一定的情况下,物种的差异也会影响到密码子的使用偏性,在进化上亲缘关系较近的物种间,其相对密码子使用概率也较接近。

78 、Here's a codon of three bases and that will give us an amino acid, which we give another single letter code to.─── 这是三个碱基组成的一个密码子 它代表一种氨基酸 我们给它一个单字母代码

79 、Prion protein codon 129 genotype preva-lence is altered in primary progressive aphasia───原发进行性失语患者的朊蛋白密码子129基因型患病率改变

80 、Keywords p53 codon 72;polymorphism;homozygote;heterozygote;HPV-associated cervical cancer;───多态性;纯合子;杂合子;HPV有关的宫颈癌;

81 、In human cDNA sequencing projecs, it is vital to know whether the first ATG codon is a real start codon or an in frame Met codon without initiation function.───在人类cDNA序列确定全长基因的过程中 ,必须判断第一个ATG密码子是真正的起始密码子还是框内的非起始作用的甲硫氨酸密码子 .

82 、A deletion of adenosine (A), at -241 (relative to initiation codon ATG), designated as Del(A) allele, was found in Laiwu compared with Yorkshire (GenBank accession number DQ463321-22).───克隆了猪DGAT1 5’调控区的部分序列(737 bp),在-241bp(相对于起始密码子ATG)发现一处由单个腺嘌呤(A)缺失产生的新SNP位点(定义为等位基因Del(A) ) (GenBank收录号:DQ463321-22);

83 、For example, the use of speciesspecific codon optimization results in increased protein production on a per-cell basis, leading to enhanced T-cell responses and antibody induction.───例如,使用物种特异性密码子将会使每细胞单位的蛋白质产量增加,从而加强T细胞的反应和抗体的吸附。

84 、multiple codon recognition───多密码子识别, 多种密码子识别

反密码子的简并性?

分子生物学中,同一种氨基酸具有两个或更多个密码子的现象称为密码子的简并性(degeneracy)。

对应于同一种氨基酸的不同密码子称为同义密码子(synonymous codon),只有色氨酸与甲硫氨酸仅有1个密码子。

同义密码子通常只在第3位碱基上不同,这样可减少有害突变。

反密码子的简并性?

简并性:同一个氨基酸有两个或更多个密码子对应的现象。

摆动性:tRNA上的反密码子与mRNA上的密码子配对时,第一,第二位碱基严格配对,而第三位碱基配对不是很严格的现象。